Berekum Chelsea left the Cairo Military Academy Stadium last Saturday badly bruised with a 1-4 defeat handed them by Al-Ahly.
It was the Ghanaiansâ€™ first defeat in the Champions League Group stage after beating and drawing with TP Mazembe.
Ahly struck double in the first 34 minutes of the game played behind closed doors through Abdallah El-Saied and Mohammed Naguib.
The competitionâ€™s top scorer Emmanuel Clottey fulfilled his promise when he score from the spot on the stroke of half time after skipper Abdul Basit had done all the dirty work to earn the penalty.
But Clotteyâ€™s goal, which takes his tally to 12, was not enough to save his side who caved in to Waild Solimanâ€™s brace after the break.
The win places the Egyptians in a pole position to make it to the semi-final with a hundred percent record, winning previous games against TP Mazembe and rivals Zamalek in Group B.
With three games to go, Chelsea need to win their next two games in Ghana to realize their dream of advancing to the semis. They will host Ahly on the weekend of August 17 and 19.
The game ended with both sides parading 10 men after left backÂ Â Richard Kissi Boateng was sent off following a second yellow card offense before recess and Wael Gomaa in the 64th minute.
Chelsea are expected to return home today.
By Kofi Owusu Aduonum